Single molecule

“DNA-Dressed NAnopore” for complementary sequence detection

Analytical Chemistry / Biomedical Engineering / Biosensors / Hybridization / Nanofabrication / Nanotechnology / Single molecule / DNA / Nucleic acid hybridization / DNA analysis / Surface Properties / BioSensors / Nanopores / Base Sequence / Electric Conductivity / Biosensing Techniques / DNA probes / Oligonucleotides / Nanotechnology / Single molecule / DNA / Nucleic acid hybridization / DNA analysis / Surface Properties / BioSensors / Nanopores / Base Sequence / Electric Conductivity / Biosensing Techniques / DNA probes / Oligonucleotides

Fluorescence Resonance Energy Transfer between organic dyes adsorbed onto nano-clay and Langmuir–Blodgett (LB) films

Engineering / Materials Engineering / Chemical Engineering / Biochemistry / Analytical Chemistry / Design / Biofilms / Water / Molecular Biology / Fluorescence / Mast Cells / Nanotechnology / Fluorescent Dyes and Reagents / Biophysical Chemistry / Chemical Physics / Single molecule / Fluorescence Resonance Energy Transfer / Strategy / Biological Sciences / Quantum Dots / Conception / Cell line / Animals / Method / Sulfides / Physical sciences / Nanostructures / Selenium Compounds / Forster Resonance Energy Transfer / Liposomes / Membrane Lipids / Luminescence / Color Image / RSC / Structural Change / Efficiency / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Cattle / Application / Optical physics / Rats / Photochemistry and Photobiology / Fourier transform infrared spectroscopy / Sensitivity / Quantum Dot / Energy Transfer / Zinc Compounds / Bovine Serum Albumin / Tellurium / Aqueous Solution / Protein Binding / Antineoplastic Agents / Conformational Change / Fluorescent Labelling / Biosensing Techniques / Membrane Fluidity / Biochemistry and cell biology / Molecular Structure / Gentamicins / Design / Biofilms / Water / Molecular Biology / Fluorescence / Mast Cells / Nanotechnology / Fluorescent Dyes and Reagents / Biophysical Chemistry / Chemical Physics / Single molecule / Fluorescence Resonance Energy Transfer / Strategy / Biological Sciences / Quantum Dots / Conception / Cell line / Animals / Method / Sulfides / Physical sciences / Nanostructures / Selenium Compounds / Forster Resonance Energy Transfer / Liposomes / Membrane Lipids / Luminescence / Color Image / RSC / Structural Change / Efficiency / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Cattle / Application / Optical physics / Rats / Photochemistry and Photobiology / Fourier transform infrared spectroscopy / Sensitivity / Quantum Dot / Energy Transfer / Zinc Compounds / Bovine Serum Albumin / Tellurium / Aqueous Solution / Protein Binding / Antineoplastic Agents / Conformational Change / Fluorescent Labelling / Biosensing Techniques / Membrane Fluidity / Biochemistry and cell biology / Molecular Structure / Gentamicins

“DNA-Dressed NAnopore” for complementary sequence detection

Analytical Chemistry / Biomedical Engineering / Biosensors / Nanotechnology / Single molecule / DNA / Nucleic acid hybridization / DNA analysis / Surface Properties / BioSensors / Nanopores / Base Sequence / Electric Conductivity / Biosensing Techniques / DNA probes / Oligonucleotides / DNA / Nucleic acid hybridization / DNA analysis / Surface Properties / BioSensors / Nanopores / Base Sequence / Electric Conductivity / Biosensing Techniques / DNA probes / Oligonucleotides

Fluorescence resonance energy transfer as a structural tool for nucleic acids

Structural Biology / Chemical Biology / Single molecule / FRET / Long Range / Nucleic Acids / DNA Structure / Nucleic Acid Conformation / Biochemistry and cell biology / Nucleic Acid / RNA folding / Nucleic Acids / DNA Structure / Nucleic Acid Conformation / Biochemistry and cell biology / Nucleic Acid / RNA folding

Excursion of a single polypeptide into a protein pore: simple physics, but complicated biology

Molecular Biology / Temporal Resolution / Single molecule / Protein Design / Porosity / Computer Simulation / Diffusion / Peptides / Proteins / Cytochrome B / Lipid bilayers / Computer Simulation / Diffusion / Peptides / Proteins / Cytochrome B / Lipid bilayers

Phosphonic pseudopeptides as human neutrophil elastase inhibitors—a combinatorial approach

Organic Chemistry / Cystic Fibrosis / Rheumatoid Arthritis / Single molecule / Humans / Trypsin / Serine Proteases / Second Order / Gingiva / Bioorganic and medicinal Chemistry / Cell Proliferation / Biological activity / Human Fibroblasts / Serine Protease / Cell Survival / Tumor Growth / Molecular Structure / Chymotrypsin / Trypsin / Serine Proteases / Second Order / Gingiva / Bioorganic and medicinal Chemistry / Cell Proliferation / Biological activity / Human Fibroblasts / Serine Protease / Cell Survival / Tumor Growth / Molecular Structure / Chymotrypsin

Single-Molecule Transport Across an Individual Biomimetic Nuclear Pore Complex

Fluorescence Microscopy / Nanobiotechnology / Temporal Resolution / Transmission Electron Microscopy / Biophysical Chemistry / Transport phenomena / Multidisciplinary / Single molecule / Biological Sciences / Humans / Nuclear pore complex / Physical sciences / Proteins / CHEMICAL SCIENCES / Nuclear envelope / Biomimetic materials / Recombinant Proteins / Dwell Time / Electric Conductivity / Protein Transport / Transport phenomena / Multidisciplinary / Single molecule / Biological Sciences / Humans / Nuclear pore complex / Physical sciences / Proteins / CHEMICAL SCIENCES / Nuclear envelope / Biomimetic materials / Recombinant Proteins / Dwell Time / Electric Conductivity / Protein Transport

Interleukin-10 determines viral clearance or persistence in vivo

Genetics / Flow Cytometry / Single molecule / HIV / Mice / Animals / Viral Infection / T cell activation / Interleukin / Animals / Viral Infection / T cell activation / Interleukin

Superconductivity in a single-C60 transistor

Quantum Information Processing / Carbon Nanotube / Single molecule / Mathematical Sciences / Physical sciences / Proximity Effect / Electron Transport / Nature Physics / Proximity Effect / Electron Transport / Nature Physics

Electromechanical Unzipping of Individual DNA Molecules Using Synthetic Sub-2 nm Pores

Electrochemistry / Electronics / Kinetics / Biotechnology / Life Sciences / Nanocomposites / Nanoparticles / Nanotechnology / Multidisciplinary / Single molecule / DNA / Temperature / Secondary Structure / Time Factors / Very high throughput / Lipid bilayers / Dwell Time / Lipid Bilayer / Nucleic Acid Conformation / Static Electricity / Nucleic Acid / Nanocomposites / Nanoparticles / Nanotechnology / Multidisciplinary / Single molecule / DNA / Temperature / Secondary Structure / Time Factors / Very high throughput / Lipid bilayers / Dwell Time / Lipid Bilayer / Nucleic Acid Conformation / Static Electricity / Nucleic Acid

Real-Time DNA Sequencing from Single Polymerase Molecules

Kinetics / Science / Fluorescent Dyes and Reagents / Multidisciplinary / Single molecule / DNA / Nanostructures / DNA sequence design / Bit Error Rate / Real Time / Secondary Structure / Base Sequence / C-DNA Synthesis / DNA Polymerase / DNA / Nanostructures / DNA sequence design / Bit Error Rate / Real Time / Secondary Structure / Base Sequence / C-DNA Synthesis / DNA Polymerase

Mitochondrial DNA integrity is not dependent on DNA polymerase-β activity

Electron Microscopy / DNA repair / Single molecule / Mitochondrial DNA / Humans / Mutation / Mice / Animals / DNA sequence design / Enzyme / Density gradient / Neurodegenerative Disease / Base Excision Repair / Functional Testing / DNA Polymerase / Biochemistry and cell biology / Mutation / Mice / Animals / DNA sequence design / Enzyme / Density gradient / Neurodegenerative Disease / Base Excision Repair / Functional Testing / DNA Polymerase / Biochemistry and cell biology

Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma

Genomics / Multidisciplinary / Single molecule / Down Syndrome / DNA / Pregnancy / Humans / Female / Aneuploidy / Mothers / Prenatal Diagnosis / Genome sequence / Fetus / DNA sequence / Pregnancy / Humans / Female / Aneuploidy / Mothers / Prenatal Diagnosis / Genome sequence / Fetus / DNA sequence

Phosphonic pseudopeptides as human neutrophil elastase inhibitors—a combinatorial approach

Organic Chemistry / Cystic Fibrosis / Rheumatoid Arthritis / Single molecule / Humans / Trypsin / Serine Proteases / Second Order / Gingiva / Bioorganic and medicinal Chemistry / Cell Proliferation / Biological activity / Human Fibroblasts / Serine Protease / Cell Survival / Tumor Growth / Molecular Structure / Chymotrypsin / Trypsin / Serine Proteases / Second Order / Gingiva / Bioorganic and medicinal Chemistry / Cell Proliferation / Biological activity / Human Fibroblasts / Serine Protease / Cell Survival / Tumor Growth / Molecular Structure / Chymotrypsin

Intramolecular Hamiltonian logic gates

Materials Engineering / Nanotechnology / Molecular Computing / Single molecule / Computer Model / Solid State electronic devices / Quantum Dynamics / Quantum Measurement / Logic Gate / Coupling Constant / Solid State electronic devices / Quantum Dynamics / Quantum Measurement / Logic Gate / Coupling Constant

Direct RNA sequencing

Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Single molecule / Signal Transduction / Astronomy / DNA / Saccharomyces cerevisiae / Polymerase Chain Reaction / Cell Signalling / Medical Research / Very high throughput / Body of Knowledge / Earth Science / Gene expression profiling / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Single molecule / Signal Transduction / Astronomy / DNA / Saccharomyces cerevisiae / Polymerase Chain Reaction / Cell Signalling / Medical Research / Very high throughput / Body of Knowledge / Earth Science / Gene expression profiling
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